Prothrombin Complex Concentrate for Rapid Reversal of Warfarin Anticoagulation to Allow Neuraxial Blockade
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منابع مشابه
Prothrombin Complex Concentrate for Rapid Reversal of Warfarin Anticoagulation to Allow Neuraxial Blockade
The development of Prothrombin Complex Concentrates (PCCs) has led to better outcomes in patients receiving emergency reversal of warfarin. However, most published data describes the use of PCCs in the setting of major bleeding or emergent major surgery, with little information on neuraxial blockade. We describe a case of rapid warfarin reversal using PCC and subsequent surgery under spinal ana...
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Anticoagulation is very effective for primary and secondary prevention of thromboembolic events. However, questions persist about the risks and management of over-anticoagulation. The annual incidence of major bleeding in trials and cohort studies has been reported to be between 1.1% and 2.3% in patients treated with warfarin to achieve an international normalized ratio (INR) of 2.0 to 3.0. The...
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Dear Sirs, We read with interest the report of the meta-analysis performed by Dentali et al. on the adverse events after prothrombin complex concentrate (PCC) use for the emergency reversal of vitamin K antagonists (1). The authors identified a low incidence of thrombotic events and a non-significant difference between fourand three-factor PCCs at 1.8% and 0.7%, respectively. We do not wish to ...
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BACKGROUND AND PURPOSE The effectiveness of prothrombin complex concentrate (PCC) products available in the United States that contain low levels of factor VII (3-factor PCC) has not been tested. The purpose of this study was to review our experience with 3-factor PCC (Profilnine) in the setting of warfarin-associated intracranial hemorrhage (wICH). METHODS In November 2007, we implemented a ...
متن کاملUse of prothrombin complex concentrate in warfarin anticoagulation reversal in the emergency department: a quality improvement study of administration delays
BACKGROUND Quick reversal of warfarin anticoagulation is important in life threatening bleeding. The aim of this study is to improve the administration delay when using Prothrombin Complex Concentrate (PCC) for the emergent reversal of warfarin anticoagulation in the emergency department. METHODS An audit and feedback quality improvement project was conducted in three phases: a retrospective ...
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ژورنال
عنوان ژورنال: Case Reports in Anesthesiology
سال: 2014
ISSN: 2090-6382,2090-6390
DOI: 10.1155/2014/126864